Vitamin D3: Deficiency, Disease and Dosing

Vitamin D3: Deficiency, Disease and Dosing

Read this, if nothing else:

Vitamin D3 deficiency has been linked to increased prevalence of cancer, hypertension, insulin resistance, depression, epilepsy, polysystic ovary syndrome, osteoarthritis and musculoskeletal pain, inflammation and autoimmune diseases. Supplementation of D3 is an easy and inexpensive way to promote health and prevent disease in children and adults. Have your doctor check your 25(OH)D3 levels at your next check-up and supplement with a quality D3 product. Optimal levels are believed to range from 60-80nmol.L.

Maintenance supplementation for infants/children: 1000 IU/day

Maintenance supplementation for adults: 5000 IU/day

- Higher dosing may be necessary to achieve optimal ranges

 

What You Need to Know about D

What if I told you that there was a supplement that is beneficial to every single cell in your body? So beneficial in fact, that it has a positive role in longevity, bone health, autoimmune conditions, depression, neurological and cognitive function, pregnancy health, inflammation, organ and organ system health.

Fortunately for us, there is a vitamin that exists that called cholecalciferol, or Vitamin D3 that has all of these health promoting effects, and it’s benefits have hovered under the radar for far too long. Simply calling D3 a “vitamin” wouldn’t do justice to it’s pro-hormone (hormone producing) role in the body, nor would it’s classification as the “anti-rickets and bone-health” vitamin. In fact, the research is indisputable that Vitamin D3 supplementation is essential.

It seems to me that if a pharmaceutical company had the ability to produce such a compound, they would tout it as having the ability to improve the health of every single person in the world while simultaneously reducing the risk of some of the most widespread diseases. Not only would it be effective, there would be no negative side effects and the cost to you would be less than 20 cents/day.

 

Vitamin D Deficiency

Vitamin D is produced in the skin by the absorption of sunlight. Those that live in Northern latitudes (North of Los Angeles), synthesis of vitamin D is reduced. Couple this with spending the majority of our time indoors, or wearing excessive coverings and sunglasses and vitamin D exposure is significantly further reduced. Additionally, sunscreen of SPF 8 reduces synthesis by 95%.

“Vitamin D deficiency is a highly prevalent condition, present in approximately 30% to 50% of the general population.”

-       J Am Coll Cardiol. 2008 Dec 9;52(24):1949-56

The current blood serum norms for 25(OH)D3 range from 30-50nmol/L, however, increasing research suggests much higher blood norms may be necessary (80-100nmol/L) for greater health benefits. This would suggest that the percentage of Americans deficient in Vitamin D3 is far higher than what research shows.

In my clinical practice, introducing D3 supplementation is one of the cheapest and most effective ways to improve body composition, improve strength, and optimize detoxification. There is no point venturing into comprehensive protocols if this foundational health need is not being potentiated.

 

Consequences of Vitamin D Deficiency

Vitamin D3 deficiency has been linked in the research to the prevalence of all of the below conditions, but more importantly “vitamin D has important benefits in reducing the risk of many conditions … includes many types of cancer, cardiovascular diseases, diabetes mellitus, several bacterial and viral infections, and autoimmune conditions such as multiple sclerosis.” – Prog Biophys Mol Biol. 2009 Mar 3

Long-term vitamin D deficiency may play a role in:

  • Cancer
  • Hypertension
  • Insulin resistance
  • Depression
  • Epilepsy
  • Polysystic ovary syndrome
  • Osteoarthritis and musculoskeletal pain
  • Inflammation and autoimmune diseases

Vitamin D Requirements

It has been shown that in regions where autoimmune disease is uncommon, sun exposure provides 10,000IU/day of vitamin D which achieves serum 25(OH)D3 of 105 – 163 nmol/L.

Because a large percentage of people throughout the world, but especially in the US are deficient, and sunlight exposure is limited, a MINIMUM of 1,000 to 2,000IU/day of D is required for maintenance > 75nmol/L

To elevate levels within the maintenance to high normal, MINIMUM of 5,000 IU/day is recommended

Adults: Use 5,000 IU per day for the greatest benefit

Infants/Children: Use 1,000 IU/day

 

Bottom Line on Vitamin D3 Supplementation

If your D levels are low, you’re more likely to die from all cause mortality.

 

How do I know what supplement to look for:

Look for Vitamin D3 (cholecalciferol) and is best purchased from a trusted health practitioner rather than the local drugstore or costco.

Bio-D Mulsion Forte is the best Vitamin D product on the market.

For maximum benefit, supplementation should be continued for a minimum of 5-9 months and should be continually re-measured via blood tests from a qualified health practitioner.

If you think you may be Vitamin D deficient or are interested in a quality Vitamin D supplement to help you maintain optimal health, contact Body Systems to discuss your options.

Note: It is important that people take the initiative to start to understand what their blood tests results mean and what is being tested for. If your doctor is not currently testing for Vitamin D3, or serum 25(OH)D3, then you need to request that they do so. It is an incredibly valuable marker for overall health and disease prevention. I suggest every client get their D3 levels tested every 3-6 months to determine how effective their D3 supplementation is. Most insurance will now cover the cost of the test, however, if not, the low cost is well worth paying for.

 

References:

  1. http://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
  2. http://www.bioticsresearch.com/system/files/LIT-079%20Bio-D-Mulsion%20%2526%20Forte%20INHOUSE.pdf
  3. http://www.bioticsresearch.com/sites/default/files/Vitamin%20D%20Desired%20Serum%20Level%20Aloia.pdf
  4. http://www.bioticsresearch.com/sites/default/files/Vitamin%20D%20Deficiency%20Holick.pdf
  5. http://www.charlespoliquin.com/ArticlesMultimedia/Articles/Article/754/Low_in_Vitamin_D.aspx